Critique of the ARDSNetwork Experimental Design, Implementation, and Reporting

John H. Noble, Jr., Ph.D
AHRP Board Member

Table 3. Estimated Cumulative Death Rates (Percent) Assuming Lowest Percent of Attrition/Missing Data for the Low and High Tidal Volume Groups in Table 2 Above Reflects Mortality and Not Random Data Collection Failure
Day 1 Tidal Volume Level Day 3 Tidal Volume Level Day 7 Tidal Volume Level
Low High Low High Low High
9.7 5.4 31.9 28.4 58.1 58.3

 

Low-High Group Death Rate Difference (Percent Low Minus Percent High):
Day 1 4.3%
Day 3 3.3 %
Day 7 -0.6 %
Day 1 - 7 4.9 %

 

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