When invited to become subjects in a medical experiment, most African-Americans decline; the memory of Tuskegee is indelibly ingrained in their communal memory. Their distrust is buttressed by the evidence; before and since Tuskegee. This community has been subjected to a continuum . . . Continue reading →
“The whole discipline of biomedical ethics rises from the ashes of the Holocaust…” Arthur Caplan The Nuremberg Code (1947) laid the foundation for biomedical ethics mandating that medical experiments conducted on human beings must conform to well-defined humane, ethical standards; foremost is . . . Continue reading →
National Institute of Mental Health (NIMH) inaugurated the “Decade of the Brain” and sponsored Psychiatry’s Cruel and Inhumane Research Paradigm In the 1980s and 1990s increased federal funding accelerated clinical research into mental disorders. History has demonstrated that mental patients are most . . . Continue reading →
1980: U.S. documents reveal criminal human experiments conducted by Japan’s Unit 731 American journalist John Powell brought to public attention the criminal human experiments conducted by Japan’s Unit 731. Citing U.S. government documents that he obtained through the Freedom of Information Act, . . . Continue reading →
1990: FDA issued a waiver from informed consent for military use of experimental drugs The FDA waiver from informed consent was to permit the DOD to use unapproved, experimental drugs and vaccines on enlisted soldiers—in violation of the foremost “absolutely essential” mandatory . . . Continue reading →
1993 Kathryn Hamilton died 44 days after being enrolled in Protocol 681 at the Hutchinson Cancer Center in Seattle Siix days later, Hamilton’s doctors submitted the journal article documenting what they had known for more than a year: The primary rescue drug didn’t . . . Continue reading →
The Declaration of Helsinki defines ethical research: “In any medical study, every patient – including those of a control group, if any – should be assured of the best proven diagnostic and therapeutic method.” (1964; 1996) That standard for ethical research was . . . Continue reading →
1998: Doing Harm: Research on the Mentally Ill, a prize winning research expose by The Boston Globe In November, 1998, the first of a four-part series by Robert Whitaker and Dolores Kong shed light on the abusive research parameters of non-therapeutic experiments conducted . . . Continue reading →
1999: Experiments on the most vulnerable The research community has consistently demonstrated its disregard for individual patient-subjects’ safety. 1999: One hundred babies are test subjects of the drug, Propulsid One hundred infants were enrolled by Dr. Susan Orenstein at Children’s Hospital . . . Continue reading →
According to the U.S. Environmental Protection Agency’s own scientific assessment reports (2004, 2009), Ultrafine particles (UFP) are considered more dangerous than PM2.5. EPA has determined that UFP can cause sudden death. “there is strong epidemiological evidence linking short-term (hours, days) exposure to PM2.5 . . . Continue reading →
Several major government-sponsored experiments conducted at major academic institutions highlight increasingly inappropriate clinical trial designs that disregard the individual survival needs of critically ill patients who cannot give or refuse consent to research. Their incapacity is exploited in experiments that increase the . . . Continue reading →
2000: Office of Protection from Research Risks (OPRR) was shifted from NIH jurisdiction to the Department of Health and Human Services (DHHS), and was renamed Office of Human Research Protection (OHRP). OHRP posts letters of determination following investigations into ethical violations. See . . . Continue reading →
National Bioethics Advisory Committee Report: Ethical & Policy Issues in Research Involving Human Participants. The shift from “human subject” as defined by the Nuremberg Code to “participant” obscures the role & function of human subjects in medical experiments. Continue reading →
In 2003, the Veterans Affairs ordered a 90-day national “stand down” for all human subject research activities “in response to the death of subjects”; as well as use of “unqualified researchers.” In January 2004, the Director of Defense Research and Engineering (DDR&E) initiated . . . Continue reading →
2004: Traci Johnson, a 19-year-old student volunteer commits suicide in Eli Lilly’s laboratory Traci Johnson, a healthy 19-year-old Bible student who was a volunteer in Eli Lilly’s antidepressant trial of Cymbalta committed suicide at Eli Lilly’s laboratory. Ms. Johnson was found hanging . . . Continue reading →
Alliance for Human Research Protection Fri, 18 Jul 2003 Dear Dr. Campbell and others concerned about ethical research: This is in response to your July 11 comments objecting to AHRP’s criticism of the ethics of two controversial ARDS experiments sponsored by the . . . Continue reading →
2004: Abu Ghraib: photographic evidence of U.S. torture of prisoners of war In 2004, public attention was drawn to the Abu Ghraib prison in Iraq because of the graphic photographs documenting depraved sadistic cruelty. The photographs had been taken by soldiers who . . . Continue reading →
On March 10, 2004, The ALLIANCE FOR HUMAN RESEARCH PROTECTION (AHRP) filed a complaint with both the Food and Drug Administration and the federal Office of Human Research Protection (OHRP) when we learned that 36 Phase I and Phase II AIDS drug . . . Continue reading →
Historically institutionalized children and prisoners have been exploited and subjected against their free will, as human guinea pigs in all manner of medical experimentation. Researchers’ regard “Criminals in our penitentiaries are fine experimental material . . . Continue reading →
Today’s New York Times Magazine cover story, Planet of the Retired Chimpanzees By Charles Siebert, reports that chimpanzees who have served as subjects in biomedical research can look forward to being set free in one of 12 specially built chimp sanctuaries the . . . Continue reading →
The efforts of AHRP to hold the medical research community and government administrators accountable for unethical exploitation of vulnerable children in medical experiments conducted in violation of federal regulations. Continue reading →
Scientists and entrepreneurs have tried for years to develop a safe and universal blood substitute that did not spoil after 42 days. However, all such efforts have encountered serious safety problems.
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TGN1412 stimulated the immune system’s T-cells to catastrophic levels; the experiment nearly killed all human subjects. All human subjects in a Phase I drug trial testing a genetically engineered experimental monoclonal antibody drug, TGN1412, face life-threatening multi-organ failure. Continue reading →
UK Patients Used as Drug ‘Guinea Pigs”_Guardian Feb 9 2003 Medical fraud experts in the U.K. estimate that one per cent of all drug trials involve fraud, including failure to get proper consent from patients. An investigation by The Guardian / Observer . . . Continue reading →
Editor of New England Journal of Medicine defends catastrophic experiments, and the Institute of Medicine expands prison drug trials. Question: How many times have these members of the elite put their own life at risk “to advance our knowledge?” Continue reading →
Background: Between 1985 and 2005, at least 532 infants and children in New York City were conscripted as human subjects of clinical trials testing experimental AIDS drugs and vaccines. The New York City Agency for Child Services (ACS), the custodian of foster . . . Continue reading →
2010: U.S. Inspector General report: 78% of human subjects in clinical trials lived outside the U.S. The Inspector General of the Department of Health and Human Services report found that 78% of human subjects in drug trials lived outside the U.S where . . . Continue reading →
Whose children are to be selected for morally and legally impermissible medical experiments? Continue reading →
Federal Investigation of ARDS Study (Accute Respiratory Distress) OHRP conducted a compliance oversight evaluation of the 12 major sites participating in this clinical trial. OHRP’s determination letters documenting the outcomes of these evaluations can be viewed at the OHRP website at the . . . Continue reading →
Acute Respiratory Distress Syndrome – ARDSNet experiment criticized – OHRP Fri, 28 Feb 2003 An Acute Respiratory Distress Syndrome (ARDS) study conducted between 1996 and 1999, on critically ill patients at 20 medical facilities (14 major research centers belonging to the ARDS . . . Continue reading →
