TGN1412 stimulated the immune system’s T-cells to catastrophic levels; the experiment nearly killed all human subjects. All human subjects in a Phase I drug trial testing a genetically engineered experimental monoclonal antibody drug, TGN1412, face life-threatening multi-organ failure.

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UK Patients Used as Drug ‘Guinea Pigs”_Guardian Feb 9 2003 Medical fraud experts in the U.K. estimate that one per cent of all drug trials involve fraud, including failure to get proper consent from patients. An investigation by The Guardian / Observer (UK) found widespread abuse by doctors who use patients as guinea pigs to…

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2010: U.S. Inspector General report: 78% of human subjects in clinical trials lived outside the U.S.  The Inspector General of the Department of Health and Human Services report found that 78% of human subjects in drug trials lived outside the U.S where safeguards and inspections are rare; 13,000 Peruvians were subjects in clinical trials where…

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Federal Investigation of ARDS Study (Accute Respiratory Distress) OHRP conducted a compliance oversight evaluation of the 12 major sites participating in this clinical trial. OHRP’s determination letters documenting the outcomes of these evaluations can be viewed at the OHRP website at the following URLs: Note: OHRP found that federal informed consent requirements had been violated…

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Acute Respiratory Distress Syndrome – ARDSNet experiment criticized – OHRP Fri, 28 Feb 2003 An Acute Respiratory Distress Syndrome (ARDS) study conducted between 1996 and 1999, on critically ill patients at 20 medical facilities (14 major research centers belonging to the ARDS Network), was published in The New England Journal of Medicine (NEJM) in 2000.…

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