1942: Edward Cohn, MD, a Harvard biochemist injected prisoners with beef blood

Edward Cohn, MD, a Harvard biochemist injected 64 Massachusetts prisoners with beef blood in an experiment sponsored by the U.S. Navy. The antigenic irritants in bovine serum albumin could not be purified away biochemically, dooming the medical utility of the bovine protein for the casualties of war. The rejection of the blood was catastrophic. (Pepper & Cina)