1950: Two-hundred female prisoners infected with viral hepatitis

1974: President Nixon signed the National Research Act establishes National Commission for the Protection of Human subjects, requiring Public Health Service to promulgate regulations for the protection of human subjects. Title 45 of the Code of Federal Regulations, later known as “The Common Rule,” requires the appointment and utilization of…

1966: Bacillus Globigii released into New York subway tunnels in an Army–CIA field study Bacillus Globigii was released into New York subway tunnels in an Army / CIA field study, exposing thousands of civilians. (Operation Bacterium) US Government Admits Testing Biological Agents on US Cities.

Syphilis experiments in Guatemala were funded by the US Public Health Service (PHS) and the National Institutes of Health (NIH) to the Pan American Sanitary Bureau (later renamed Pan Am Health Org.) The US team of researchers in Guatemala was led by John Charles Cutler, MD of the PHS who…

Dr. Chester Southam injected live cancer cells into 22 elderly patients at Jewish Chronic Disease Hospital in Brooklyn. After being rebuffed by his institution, Sloan-Kettering, he convinced Dr. Emanuel Mandel at Jewish Chronic Disease. He sought to learn whether people who were debilitated by cancer could reject cancer cells. None…

Chester M. Southam, MD, a noted immunologist at Sloan-Kettering Institute sought to study the human immunity response to cancer. He obtained funding from the government and injected live cancer cells into 14 patients with advanced cancer and into healthy convicts at Ohio State Prison. The study in prisoners was designed…

1958–1962: An Atomic Energy Commission field study — “Project Chariot” — spread radioactive materials over Inupiat land in Point Hope, Alaska. Today, cancer is the leading cause of death in Point Hope. Alaska Dispatch, 2012.