May 27

Brazilian Scientists Speak Out Against Corrupted “Science” & the Use of Inhumane Study Methods

The COVID-19 pandemic has been exploited by government-sponsored medical scientists who dispensed with foundational international medical ethics standards that were adopted by the world community following the revelations of wartime Nazi medical atrocities. The Nuremberg Code of 1947 is part of the legal verdict against the Nazi doctors on trial at Nuremberg.

Vulnerable elderly human beings are at greatest risk of death; not only from this unnatural, most likely laboratory-crafted virus, but they have been subjected to draconian government-dictated inhumane policies that condemned large numbers of them to death by denying them life-saving treatments in hospitals. New York State Governor Andrew Cuomo, issued an infamous March 25th directive ordering ill-equipped nursing homes to accept infected elderly people; thereby condemning more than 4,500 people at those facilities to die.  [NYS Department of Health removed the directive from its website. See Associate Press, New York Post]

COVID-19 has generated a series of unethical, scientifically dubious experiments in an effort to invalidate the use of Hydroxychloroquine (HCQ). The protocols of these studies were crafted in ways that skewed the therapeutic effect of this medicine that has been in use for more than 70 years. These experiments resulted in the predictable death of the elderly human subjects. These unethical experiments were conducted by dozens of academic scientists. They were rapidly “peer reviewed” and published in the premier international scientific journals.

Why were the HCQ studies deliberately skewed? Because this unpatented, cheap (practically free) medicine – that has been shown to work when administered early and in proper doses – poses a very substantial financial threat to those who seek to corner the market with a not-yet-formulated drug and/ or vaccine –  that will generate not merely billions of dollars, but trillions of dollars. Bill Gates publicly declared that “the Final Solution” for COVID-19 will be a vaccine.

How could the dubious protocol designs have escaped the peer reviewers ? 

We salute the Brazilian scientists and academics who have come forward with a scathing Open Letter that Speaks Truth to Power.   “For the truth shall set you free”.

Part of that rarely acknowledged truth, is that scientists’ opinions are not necessarily guided by “science”. When confronted with a strongly disputed issue,  scientists , like everyone else who takes sides, make their choice based on personal preferences and self-interest.  As acknowledged in the Open Letter bellow: “Scientists are people and people have likes and dislikes, passions and political party preferences.

UPDATE June 2, 2020. More than 200 prominent scientists across the world signed an Open Letter addressed to the authors of a highly publicized, influential report published in The Lancet, May 22, 2020, and to the editor, Dr. Richard Horton.  The authors of the report are: Mandeep R Mehra, MD, Sapan S Desai, MD, Prof Frank Ruschitzka, MD, Amit N Patel, MD,

The roster of scientists who signed the letter specifying at least 10 serious irregularities and inaccessible data owned by one of the lead co-authors,  provides added credibility to the concerns raised by the Brazilian scientists.
Read The Lancet Published a Fraudulent Study: the Editor Calls it “Department of Error”

Brazilian scientists and academics write an Open Letter Challenging  the “science” of the coronavirus pandemic, CONNEXÃO POLITICA,  May 25, 2020

The coordinator of the statement is Professor Marcos Nogueira Eberlin, a member of the Brazilian Academy of Sciences. He holds a PhD in chemistry from the University of Campinas. After postdoctoral work at Purdue, Dr. Eberlin founded the Thomson Mass Spectrometry Laboratory, growing it into a highly distinguished lab where he supervised some 200 graduate and post-doctoral students and scientists who today work as researchers and professionals all around the globe.

Professor Eberlin is the winner of the prestigious Thomson Medal (2016) and the former president of the International Mass Spectrometry Foundation, He is recognized worldwide as one of the most productive mass spectrometrists ever, having published close to 1,000 scientific articles. He discovered the Eberlin Reaction during his work on gas phase ion chemistry, and he and his research group introduced EASI (Easy Ambient Sonic-spray Ionization), an ionization technique used in mass spectrometry.

Full text of the open letter: [All highlights by VS]

The “science” of the Pandemic

During this pandemic, the term “science” has been used “ad nauseam”, that is, has been repeated to exhaustion: “Science, science, science”, “I’m pro-science”, “For from the science, through the science and to the science I guide my decisions and acts” and “I am, therefore, fully right to do so”. It is clear that the intention here is to lead all of us to the idea of ​​decisions based on something unquestionable and infallible, as scientific as law, as the law of gravity.

Groups of “science experts” or famous YouTube scientists, many of them still “beginners” in science, some of them with a minimal or no experience in fighting pandemics, are selected by the establishment and the media to give “scientific aura” for the lockdown and the condemnation of hydroxychloroquine (HCQ) as an ineffective drug; worse, as a deadly poison.

That disastrous apocalyptic simulations from the “Imperial College” – this pompous name that brings us to the idea of ​​a center of excellence of infallible, omnipotent and unquestionable knowledge, an “College of the Empire” – are being used to place everyone at home, and then, to compare data as being the absolute reference of the truth. “We did something and as a result, we reduced those many deaths. Therefore: ‘blessed be the science!’”.

But what kind of “science” is that to which they are appealing? And who, in the name of this “science”, would be allowed to speak? Science (I know that there are controversies, as scientists even debate on its meaning) is “the dispassionate search for the truth about the Universe and life”. But ironically, we seek truths that we don’t even know what those truths would be like, or where they would be found. For this reason, sometimes, ironically, even when scientists find a truth that is indeed true, yet they doubt that they have found it. We literally zigzag in the dark, searching for solutions to our problems. Therefore, we sometimes say that: “eating eggs is bad, it increases cholesterol”; and sometimes: “eggs are good, eat at ease”.

Richard Feynman put it this way: “Science is the culture of doubt”. And I would add, “science is the culture of debate, of divergence of opinions”.

Rarely, there are situations in which we reach consensus in science, even a momentary consensus. Some defend the “Big Bang” and the theory of evolution, others, including myself, are skeptical of them. Some defend with data and papers the central role of men in global warming, others defend, with the same data and papers, that human activity is irrelevant. Scientists are human beings, therefore, skeptics and enquirers who can and should speak for themselves, like all scientists have the right to do, but NEVER A SCIENTIST OR A GROUP OF THEM CAN DECLARE TO BE AUTHORIZED TO SPEAK IN THE NAME OF SCIENCE!

Nobody, absolutely nobody is allowed to speak for science or declare that he is “been guided” by science! In times of pandemic, this impossibility is even greater, as we face an unknown enemy. Data is still being collected and research is being performed and published by scientists divided by their worldviews, and by their political and party preferences.

Whoever said he acted in the name of science, dishonestly usurped science prestige. For what type of “science” is this, unanimous and consensual, that no one has ever heard of? Could someone give me its address so I can confirm its consent? Its phone, email and WhatsApp?

As for hydroxychloroquine (HCQ), the inevitable scientific clash between theses is clear
When renowned scientists from around the world and in Brazil – such as virologist Paolo Zanotto (with 7,400 scientific citations) and doctors Didier Raoult (with 148,000 citations), Philip M. Carlucci and Vladimir Zelenko – defend its use based on studies and articles, whereas other scientists, also renowned and based on the same or other studies and articles, condemn it.

Numerous countries such as the USA, Spain, France, Italy, India, Israel, Russia, Costa Rica and Senegal use the drug (HCQ) to fight covid-19, whereas other countries refrain from using HCQ as one of the strategies to contain the pandemic, betting on other controversial tactics.

  • Who then speaks here in the name of “science”?
  • Which group has a monopoly on reason and its exclusive authorization to be the spokesperson of “science”?
  • Where is such authorization found?

One can choose an opinion, and base his strategy on it, this is fine, but no one should commit the sacrilege of protecting his decision risking to tarnish it with the “sacred mantle of science”. Outraged, every day I hear mayors and governors saying at the top of their lungs that they “have followed science”. Presidents of councils and some of their advisers, and of academies and deans in their offices write letters on behalf of their entire community, as if they reflect everyone’s consensual position. Nothing could be more false.

Have they followed science? Not at all! They have followed the science wing which they like, and the scientists who they chose to place around them. They ignore the other wing of science, since there are also hundreds of scientists and articles that oppose their positions and measures.

Worse, scientists are not angels. Scientists are people, and people have likes and dislikes, passions and political party preferences. Or wouldn’t they? There are many scientists, therefore, who do good without looking at whom, I know and admire many of them. But there are also pseudoscientists who use science to defend their opinion, their own pocket, or their passion. Scientists have worked and still work hard and detached to contribute to the good of humanity, many of whom are now in their laboratories, risking their lives to develop new methods of detecting coronavirus, drugs and vaccines, when they could stay “safe at home”.

But, to illustrate my point, I know scientists who have published articles, some even in major journals such as “Science” or “Nature”, with data they have manufactured “during the night”; others who have removed points from their curves, or used other similar strategies.

  • Many scientists were at Hitler’s side, weren’t they? Did they act in the name of “science”?
  • Others have developed atom bombs.
  • Others still develop chemical and biological weapons and illicit drugs, by design.

The Manaus’ study with chloroquine (CQ) performed here in Brazil and published in the Journal of the American Medical Association (JAMA) [1], is emblematic to this discussion of “science”. The  manuscript reveals that:

  • Scientists used lethal doses in debilitated patients, many in severe conditions and with comorbidities.
  • The profiles of the groups do not seem to have been “randomized”, since a clear “preference” in the HIGH DOSE group for risk factors is noted.
  • Chloroquine, which is more toxic than HCQ, was used.
  • and it seems that they even made “childish mistakes” in simple stoichiometric calculations, doubling the dosage with the error.

I’m incapable of judging intentions, but justice will do it.
The former Brazilian Health Minister Luiz Henrique Mandetta quoted this study, supported it, and based on it, categorically stated: “I do not approve HCQ because I am based on ‘science, science, science’!”.

Another study published by Chinese researchers in the British Medical Journal (BMJ) and which is still persistently used against HCQ was also at least revolting [2]. In it, the authors declared: “we administer 1,200 mg for 3 days, followed by 800 mg for 12 to 21 days, in patients with moderate to severe symptoms”.

In other words, they gave a huge dosage of the drug that could reach the absurdity of 20 grams in the end, and it given was too late to patients (HCQ should be administered in the first symptoms or even earlier). And even worse, overdosing on HCQ or any other drug for severe cases is poisonous.

What do you think, was it good science?

The recommended dosage in Brazil, since May 20th, 2020, by the new Ministry of Health, for mild symptoms is 2 times 400 mg in the first day (every 12 hours) and 400 mg for 5 days for a total of 2.8 grams.

In other published studies, also in these internationally renowned journals such as The New England Journal of Medicine, JAMA and BMJ [3-5], once again, “problems” are clearly noted, [sic] patients were randomized in irregular ways, placing older, more susceptible or most severe and hypoxemic patients in the higher (lethal) dose groups.

  • more men [for whom covid is] almost 3 times more deadly [sic] than for women,
  • or more black people (in the USA, black people have displayed higher mortality)
  • and more smokers. 
  • Most of the deaths occurred in the first days of the studies (signs that these deaths were of critically ill patients, who at this stage would be more “intoxicated” than “treated” with HCQ). They also  administered HCQ alone, when it is known that it is necessary to combine HCQ at least with azithromycin.

One of these studies [5] administered HCQ only on the sixteenth day of symptoms (for really early treatment, HCQ administration should be started up to fifth day), in other words, [they administered the drug only]  at the end of the disease, when the drug can do little good or nothing to the patient.

  • These studies indicate that some scientists either forgot how “science” is done or that there is a huge effort to disprove, whatever it takes, that HCQ works.
  • How can someone or even Councils and Academies of Medicine cite such studies as the “science” of their decisions? How can that be?

On the contrary, the study is published – and today with more than 3 thousand patients tested – and carried out by Dr. Didier Raoult in France [6], using the correct dosage and at the right time, with a very low mortality rate (0.4%), and the Prevent Senior’s clinical experience in Brazil – also quite encouraging – are disqualified with very “futile” arguments such as:

  • “Didier Raoult is a controversial and unworthy researcher”;
  • “At Prevent Senior Clinic they were not sure of the diagnosis” (but none of the hospitalized patients with clear COVID symptoms died);
  • “Placebo effect” (what a supernatural power of inducing our mind that reduces mortality from 40% to zero, I want this placebo!);
  • “Study performed by a health plan company”
  • (I do not doubt that this people indeed want to save lives, because the patients were their customers who pay their bills), and similar ephemeral arguments.

I post on my Facebook, almost daily, works, studies and incredible reports in favor of HCQ. Many sympathize with me, but some are vehemently opposed, and confront me with arguments such as: “how can such a respected scientist lose his prestige to defend such a president [Bolsonaro]?”. Some of them I know personally, others I search on their profiles. They may exist, I know, but I haven’t found even one of these Facebook friends so far who is not a leftist, fight against the current president of Brazil and, as a rule, is in favor of the clumsy #StayAtHome.

But the most important question I think [that] should be asked is this:
Are we absolutely certain by “science” that HCQ is efficient and saves lives? No, we are not. The chance is high, but certainly no scientist is sure about it. In a few years, we will know better.

Are we then absolutely certain today that HCQ does not work? Of course we are not, no one honestly is certain of it. Therefore, I want to leave the “science of doubt” aside, since scientists diverge, and appeal to another area: the law. Here in Brazil the use of HCQ has even been questioned to the supreme court asking judges to settle the debate based on “science”. Nobody knows, however, who will speak “in the name of science”. But there is, in Law, a unquestionable and consensual position that could be used to define the dilemma:

“In dubio pro reo”. In other words, in case of doubt, favor or absolve the defendant (in this case, the HCQ).

If there is doubt by “science”, and a plausible possibility is the cure with HCQ, and if the drug is cheap (nearly free), available and distributed by several pharmaceutical companies ( in Brazil by Cristália, Apsen, EMS, Armed Forces , Sanofi-Aventis), and since it has minimal side effects in acute dosages of only 5 days (many take the drug daily for years), similar to all drugs (see aspirin and paracetamol), and considering that the  [patient] is likely to face a higher risk of [death], if not medicated, then we should all be PRO-LIFE!

THAT ALL, ABSOLUTELY ALL BRAZILIANS WHO WISH TO DO SO SHOULD HAVE THE RIGHT TO BE TREATED WITH HCQ.

It’s a fair legal decision. And that is it.

This is science, not the “science” that I like or the “science” that others have appropriated it, but the “science” that we have here and now, based on the current facts, based on reason.

Finally, let us all remember that in the face of a new disease and its extremely rapid progression in the most debilitated patients with very serious complications, and so many uncertainties in the diagnosis, and as we don’t treat papers or health forms, but PEOPLE, it is imperative to the doctor look face to face [at] their patients and decide [to invoke] not the “science of some”, but the valuable compass of medicine that has saved many lives since the beginnings of medicine: “THE CLINIC IS SOVEREIGN!”

Prof. Marcos N. Eberlin

Email: mneberlin@gmail.com

Open Letter signed by:

Amilcar Baiardi, Catholic University of Salvador – UCSAL, 2,500 citations

Bento João da Graça Azevedo Abreu, Federal University of Rio Grande do Norte, 77 citations

Carlos Adriano Ferraz, Federal University of Pelotas – UFPel, 8.7 thousand citations

Donato Alexandre Gomes Aranda, Federal University of Rio de Janeiro, 3,600 citations

Elvis S. Böes, Federal Institute of Brasília, 686 citations

Esteban Lopez Moreno, Federal University of Rio de Janeiro, 302 citations

Heloísa Candia Hollnagel, Federal University of São Paulo

Jaime Henrique Amorim, Federal University of Western Bahia, 407 citations

José Roberto Gomes Rodrigues, State University of Bahia

Kin Shung Hwang, no affiliation

Laércio Fidelis Dias, Paulista State University 288 – UNESP, 125 citations

Leonardo Vizeu Figueiredo, Federal Fluminense University – UFF, 280 citations

Luciano Dias Azevedo, Docentes Pela Liberdade, physician

Marcelo Henrique Napimoga, without affiliation, 3.8 thousand citations

Marcelo Hermes Lima, University of Brasilia (UnB), 6.3 thousand citations

Marcos N. Eberlin, Mackenzie Presbyterian University (UPM), 25.2 thousand citations

Ney Rômulo de Oliveira Paula, Federal University of Piauí, 150 citations

Pablo Christiano Barboza Lollo, Federal University of Grande Dourados, 1,100 citations

Pedro Jorge Zany P. M. Caldeira, Federal University of Triângulo Mineiro, 65 citations

Paulo Roberto Ferreira Louzada Junior, Federal University of Rio de Janeiro, 3.1 thousand citations

Peterson Dayan Machado Goncalves, Institute of Higher Education of Brasília

Rafael Jose de Menezes, Catholic University of Pernambuco

Rodrigo Caiado de Lamare, PUC-RJ and University of York, 11.5 thousand citations

Rosivaldo dos Santos Borges, Federal University of Pará, 761 citations

Rui Seabra Ferreira Junior, Paulista State University (Universidade Estadual Paulista – UNESP), 1.3 thousand citations

(The researchers who sign the letter add up to more than 69,000 citations.)

References:
[1] –  https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765499
[2] – https://www.bmj.com/content/369/bmj.m1849https://www.nejm.org/doi/full/10.1056/NEJMoa2012410
[3] – https://jamanetwork.com/journals/jama/fullarticle/2766117
[4] – https://www.bmj.com/content/369/bmj.m1844
[5] – https://www.bmj.com/content/369/bmj.m1849
[6] – https://pubmed.ncbi.nlm.nih.gov/32387409/

 

The Portuguese version of the open letter can be read here


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