1714: Charles Maitland, Smallpox
Dr. Maitland inoculated six prisoners with smallpox, promising them release from prison. (Read D. Wooton, Bad Medicine: Doctors Doing Harm Since Hippocrates, 2006.)
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Reference Sources for Experiments Prior to World War II
Advisory Committee on Human Radiation Experiments (ACHRE) Report Ch. 2, 1995. Lawrence Altman. Who Goes First? The Story of Self-Experimentation in Medicine, 1988 Appeal from the Lübeck Decision, Journal of the American Medical Association (JAMA), 1932 Nicholas Bakalar. Where the Germs Are: A Scientific Safari, 2003 Edwin Black. War Against…
1927: U.S. Supreme Court upheld sterilization statute
U.S. Supreme Court upheld a Virginia forced sterilization statute of people considered “genetically unfit.” Harvard-educated eugenicist, Oliver Wendell Holmes’ infamous declaration, “Three generations of imbeciles are enough. . .” resulted in the forced sterilization not only of Carrie Buck of Charlottesville, Virginia, who was falsely “diagnosed” as mentally deficient and…
1930s — 1940s: William C Black, MD conducted herpes experiments on children
William C Black MD conducted unethical medical experiments on children. He wrote a report about an experiment in which he had infected a 12-month old baby with herpes. Francis Payton Rous, editor of the Journal of Experimental Medicine, rejected Black’s manuscript and wrote an editorial in the Journal stating: “I cannot…
1900–1930: Berlin Code of Ethics
Biomedical research in Germany was considered the most advanced in the world — both in its development and its ethics standards. Berlin Code of Ethics (1900) guaranteed that “all medical interventions for other than diagnostic, healing, and immunization purposes, regardless of other legal or moral authorization are excluded under all…
American Eugenics Research — Racism masquerading as “science”
“Whatever the motives and methods used to realise them – persuasion, education, coercion, sterilisation, segregation, euthanasia and more – eugenics has stemmed from the belief that a population, ‘race’, or even the species, is ‘degenerating’ and in urgent need of improvement and revitalisation.” (Prof. John Galloway. Review, The Oxford Handbook…
1930s: Antivivisectionists campaign against wide use of children as guinea pigs
William C. Black, MD, selected at random, 23 children from his patients and injected them with infected herpes tissues to demonstrate symptoms that were caused by a single herpes virus. (Timothy Murphy, The Ethics of Research with Children, AMA, 2003) M Hines Roberts described in a major medical journal an…