William C Black MD conducted unethical medical experiments on children. He wrote a report about an experiment in which he had infected a 12-month old baby with herpes. Francis Payton Rous, editor of the Journal of Experimental Medicine, rejected Black’s manuscript and wrote an editorial in the Journal stating:
Dr. Payton Rous 1966 Nobel Prize Winner
“I cannot let this occasion pass without saying that in my personal view th inoculation of a twelve month old infant with herpes virus obtained from an adult was an abuse of power, an infringement of the rights of an individual, and not excusable because the illness which followed had implications for science. The statement that the child was ‘offered as a volunteer’ – whatever that may mean – does not palliate the action.(Rous, 1941, quoted by Michael Grodin and Leonard Glanz. Children as Research Subjects: Science, Ethics, and Law, 1994)
Nevertheless, Black published his report in the Journal of Pediatrics, 1942. Black selected at random, 23 children from his patients and injected them with infected herpes tissues to demonstrate symptoms that were caused by a single herpes virus. (Timothy Murphy. The Ethics of Research with Children, AMA, 2003)
Dr. Rous received the Nobel prize 50 years after he discovered the transmittable virus causing sarcoma cancer in chickens, but his discovery had been rejected by most pathologists. For about forty years his momentous discovery had little impact, because scientists were not prepared to think of viruses as agents of cancer.
Dr. Armauer Hensen, a Norweigian microbiologist who discovered the bacterium that causes leprosy, having failed to grow the bacterium in a petri dish or any experimental animal, he tried to inoculate leprosy into the eye of a woman without her consent or knowledge. In 1880, she sued him in a…
Germany’s Ministry of the Interior issued “Guidelines for Human Experimentation” Unambiguous informed consent is mandatory; particular care must be taken when the subject is a child under 18; exploitation of patients who poor, or socially disadvantaged is prohibited; disclosure requirements — the purpose, justification, and the manner in which research…
“Leaders of the American Medical Association briefly considered amending the organization’s code of ethics to include the provision that human experimentation calling for the knowledgeable permission of the subject. The AMA leadership decided not to adopt such a stance believing it both unnecessary in light of the good moral character…
Lubeck, Germany: 240 infants were vaccinated with the Calmette tuberculosis vaccine during the first 10 days of life: almost all developed tuberculosis and 72 infants died from contaminated live BCG tuberculosis vaccine. Two people who had prepared the vaccine in the local laboratory went to prison for bodily injury due…
U.S. Public Health Service begins a 25-year Syphilis experiment at Tuskegee, Alabama, involving 400 black sharecroppers. The purpose of the experiment was to study the natural course of untreated syphilis in Negro men. Notwithstanding the participation of black institutions, doctors and the pivotal nurse Eunice Rivers, the underlying premise of…
J. Marion Sims performed multiple experimental surgeries on enslaved African women without the benefit of anesthesia. After suffering unimaginable pain, many lost their lives to infection. One woman was made to endure 34 experimental operations for a prolapsed uterus. Read: Wendy Brinker, 2002.
