1897: Giuseppe Sanarelli, MD

Giuseppe Sanarelli, MD, Italian bacteriologist injects the bacillus causing yellow fever five patients without their consent. Three of the five patients died. Dr. William Osler publicly admonished Sanarelli, stating: “To deliberately inject a poison of known high degree of virulency into a human being, unless you obtain the man’s sanction,…

1904: Carnegie Institution — Experimental Evolution –> Eugenics

The Carnegie Institution established the Station for Experimental Evolution at Cold Spring Harbor, under the directorship of Charles Davenport, which became the foundation for the eugenics movement. Eugenics uses pseudo-scientific techniques and hypotheses to support racism. “Historians of race and American medicine have documented over two centuries of race-based scientific…

1913–1951: Dr. Leo Stanley

Dr. Leo Stanley, chief surgeon at San Quentin Prison for forty years, performed a wide variety of unethical experiments — which were eugenics in nature — on hundreds of prisoners. He focused on rejuvenating their masculinity through two bizarre methods: sterilization, and by implanting them with “testicular substances” from executed…

1916: American Medical Association, no research ethics code

“Leaders of the American Medical Association briefly considered amending the organization’s code of ethics to include the provision that human experimentation calling for the knowledgeable permission of the subject. The AMA leadership decided not to adopt such a stance believing it both unnecessary in light of the good moral character…