October 26

"Depressionology" is Alive and Well

“Depressionology” is Alive and Well

Wed, 16 Mar 2005

When science fails to provide a rationale – there is “depressionology”

The writer has an article as well as editorial in this APA publication:

Andrew A. Nierenberg, Polina Eidelman, Yelena Wu, and Megan Joseph

Depression: An Update for the Clinician

Contact: Vera Hassner Sharav

Focus 3:1 (2005)

© 2005 American Psychiatric Association

From the Guest Editor
Andrew A. Nierenberg, M.D.

Major depressive disorder is a widespread, serious, chronic, and recurrent condition that imposes the burden of depressive symptoms and associated dysfunction and can ultimately lead to suicide. Psychopharmacological and specific psychotherapeutic interventions lessen the burden of depression, yet in modern clinical trials high placebo rates make efficacy difficult to prove. The mixed proof of efficacy has contributed to reassessments of the benefit-risk ratio of antidepressants and a reemergence of concerns that antidepressants can induce suicidality. In 2004, the Food and Drug Administration issued black box warnings on package inserts of antidepressants that, in some ways, state the obvious: patients with depression, especially children and adolescents, should be tracked carefully for exacerbations and suicidal ideation during treatment. In other words, physicians should take depression and its treatment seriously.

In this issue of FOCUS, articles highlight the strengths and limitations of data on the pathophysiology and practical treatment of major depressive disorder. On balance, the data support the continued use of antidepressants and psychotherapy for depression. Recent data elucidating the genetics, neuroimaging, and pharmacogenetics of depression, in some cases pointing toward or supporting novel treatments, confirm that the exciting area of “depressionology” is alive and well.

FAIR USE NOTICE: This may contain copyrighted (© ) material the use of which has not always been specifically authorized by the copyright owner. Such material is made available for educational purposes, to advance understanding of human rights, democracy, scientific, moral, ethical, and social justice issues, etc. It is believed that this constitutes a ‘fair use’ of any such copyrighted material as provided for in Title 17 U.S.C. section 107 of the US Copyright Law. This material is distributed without profit.

Subscribe To Our Newsletter!

Sign up and be the first to find out the latest news and articles about what's going on in the medical field.

You may also like

November 21, 2023

Vera Sharav is joining Christine Anderson as special guest for the Make It Your Business event in

Read More
Vera Sharav Joins Christine Anderson for Make It Your Business – Dec 4, 2023 in New Jersey

November 21, 2023

Vera Sharav is premiering the movie Never Again is Now Global in New York City, December 1.

Read More
Never Again is Now Global – Premiere Screening – Dec 1, 2023 in New York City