William C Black MD conducted unethical medical experiments on children. He wrote a report about an experiment in which he had infected a 12-month old baby with herpes. Francis Payton Rous, editor of the Journal of Experimental Medicine, rejected Black’s manuscript and wrote an editorial in the Journal stating:
Dr. Payton Rous 1966 Nobel Prize Winner
“I cannot let this occasion pass without saying that in my personal view th inoculation of a twelve month old infant with herpes virus obtained from an adult was an abuse of power, an infringement of the rights of an individual, and not excusable because the illness which followed had implications for science. The statement that the child was ‘offered as a volunteer’ – whatever that may mean – does not palliate the action.(Rous, 1941, quoted by Michael Grodin and Leonard Glanz. Children as Research Subjects: Science, Ethics, and Law, 1994)
Nevertheless, Black published his report in the Journal of Pediatrics, 1942. Black selected at random, 23 children from his patients and injected them with infected herpes tissues to demonstrate symptoms that were caused by a single herpes virus. (Timothy Murphy. The Ethics of Research with Children, AMA, 2003)
Dr. Rous received the Nobel prize 50 years after he discovered the transmittable virus causing sarcoma cancer in chickens, but his discovery had been rejected by most pathologists. For about forty years his momentous discovery had little impact, because scientists were not prepared to think of viruses as agents of cancer.
Luther Emmett Holt, a professor of children’s disease at Columbia University, was accused of conducting 1,000 tuberculin tests on sick and dying babies at NY Babies’ Hospital. (Grodin and Glantz, Children As Research Subjects)
Yellow fever epidemics struck the United States repeatedly in the 18th and 19th centuries. The disease was not indigenous; epidemics were imported by ship from the Caribbean. Dr. Reed decided against self-experimentation and injected 22 Spanish immigrant workers in Cuba instead with the agent for yellow fever. He paid them…
Under the undue influence of Harvard and other Ivy League eugenicists, the U.S. enacted the Immigration Restriction Act, 1924 to prevent “social inadequates” from immigrating. The established quotas according to racial and/or ethnic ancestry; and was the main tool used to prevent Jewish survivors of the Holocaust from gaining entry…
Louis Pasteur, a French chemist, microbiologist who laid the foundation for vaccines. After testing the rabies vaccine in 50 dogs, he tested the vaccine on 9-year-old Joseph Meister who was bitten by a rabid dog with a physician in attendance. The experiment was controversial and he was brought before the…
William C. Black, MD, selected at random, 23 children from his patients and injected them with infected herpes tissues to demonstrate symptoms that were caused by a single herpes virus. (Timothy Murphy, The Ethics of Research with Children, AMA, 2003) M Hines Roberts described in a major medical journal an…
Hideyo Noguchi, MD, of the Rockefeller Institute for Medical Research injected a syphilis preparation into 146 children — 100 were institutionalized and 46 were healthy — in an attempt to develop a skin test for syphilis. Several parents sued Dr. Noguchi for infecting their children with syphilis. (Noguchi. Journal of…
