1714: Charles Maitland, Smallpox

U.S. Public Health Service begins a 25-year Syphilis experiment at Tuskegee, Alabama, involving 400 black sharecroppers. The purpose of the experiment was to study the natural course of untreated syphilis in Negro men. Notwithstanding the participation of black institutions, doctors and the pivotal nurse Eunice Rivers, the underlying premise of…

Yellow fever epidemics struck the United States repeatedly in the 18th and 19th centuries. The disease was not indigenous; epidemics were imported by ship from the Caribbean. Dr. Reed decided against self-experimentation and injected 22 Spanish immigrant workers in Cuba instead with the agent for yellow fever. He paid them…

In Pennsylvania, 146 children were inoculated with syphilis in several hospitals (Sierra, 2011); and in Philadelphia’s St. Vincent’s House researchers “tested” 15 infants at with tuberculin resulting in several children becoming permanently blind. This atrocity was recorded by the Pennsylvania House of Representatives.

Biomedical research in Germany was considered the most advanced in the world — both in its development and its ethics standards. Berlin Code of Ethics (1900) guaranteed that “all medical interventions for other than diagnostic, healing, and immunization purposes, regardless of other legal or moral authorization are excluded under all…

Lubeck, Germany: 240 infants were vaccinated with the Calmette tuberculosis vaccine during the first 10 days of life: almost all developed tuberculosis and 72 infants died from contaminated live BCG tuberculosis vaccine. Two people who had prepared the vaccine in the local laboratory went to prison for bodily injury due…

Dr. Leo Stanley, chief surgeon at San Quentin Prison for forty years, performed a wide variety of unethical experiments — which were eugenics in nature — on hundreds of prisoners. He focused on rejuvenating their masculinity through two bizarre methods: sterilization, and by implanting them with “testicular substances” from executed…