William C Black MD conducted unethical medical experiments on children. He wrote a report about an experiment in which he had infected a 12-month old baby with herpes. Francis Payton Rous, editor of the Journal of Experimental Medicine, rejected Black’s manuscript and wrote an editorial in the Journal stating:
Dr. Payton Rous 1966 Nobel Prize Winner
“I cannot let this occasion pass without saying that in my personal view th inoculation of a twelve month old infant with herpes virus obtained from an adult was an abuse of power, an infringement of the rights of an individual, and not excusable because the illness which followed had implications for science. The statement that the child was ‘offered as a volunteer’ – whatever that may mean – does not palliate the action.(Rous, 1941, quoted by Michael Grodin and Leonard Glanz. Children as Research Subjects: Science, Ethics, and Law, 1994)
Nevertheless, Black published his report in the Journal of Pediatrics, 1942. Black selected at random, 23 children from his patients and injected them with infected herpes tissues to demonstrate symptoms that were caused by a single herpes virus. (Timothy Murphy. The Ethics of Research with Children, AMA, 2003)
Dr. Rous received the Nobel prize 50 years after he discovered the transmittable virus causing sarcoma cancer in chickens, but his discovery had been rejected by most pathologists. For about forty years his momentous discovery had little impact, because scientists were not prepared to think of viruses as agents of cancer.
“Leaders of the American Medical Association briefly considered amending the organization’s code of ethics to include the provision that human experimentation calling for the knowledgeable permission of the subject. The AMA leadership decided not to adopt such a stance believing it both unnecessary in light of the good moral character…
Joseph Goldberger, MD, under orders of the US Public Health Office induces Pellagra, a debilitating fatal disease affecting the central nervous system, in twelve Mississippi inmates in an attempt to discover treatments for the disease. He determined that the disease was caused by niacin (Vitamin B3) deficiency. But the Public…
The Hippocratic medical ethics oath is attributed to Hippocrates, and was adopted as a guide to the medical profession conduct throughout the ages and still used in the graduation ceremonies of many medical schools. In essence, the Hippocratic Oath: “Primum non nocere” (“First do no harm” or “Above all, do…
In a lawsuit involving the Society of NY Hospital, Justice Benjamin Cardozo ruled : “Every human being of adult years and sound mind has a right to determine what shall be done with his own body, and a surgeon who performs an operation without his patient’s consent commits an assault.” But…
Richard Strong, MD, a professor of tropical medicine at Harvard, conducted cholera experiments on 24 prisoners in the Philippines killing thirteen. Their deaths were attributed to the accidental substitution of bubonic plague serum for cholera. He rewarded the survivors with cigars. During the Nazi trials at Nuremberg, the defendants cited…
U.S. Supreme Court upheld a Virginia forced sterilization statute of people considered “genetically unfit.” Harvard-educated eugenicist, Oliver Wendell Holmes’ infamous declaration, “Three generations of imbeciles are enough. . .” resulted in the forced sterilization not only of Carrie Buck of Charlottesville, Virginia, who was falsely “diagnosed” as mentally deficient and…
