It is estimated to represent 1 in 100 adverse drug events that occur. However, as there is no control, the number of incidents do not inform us about the rate at which these events occured or possible contributing factors other than the drug.

SUICIDE ACCOMPLISHED MHRA stats from Yellow Cards 2004

Drug Substance	No of Reports
1 fluoxetine	62
2 paroxetine	38
3 clozapine	27
4 venlafaxine	17
= 5 sertraline	15
= 5 isotretinoin	15
=7 citalopram	9
=7 dothiepin	9
=7 moclobemide	9
= 10 risperidone	8
= 10 zopiclone	8
12 olanzapine	7
= 13 amitriptyline	6
= 13 mefloquine	6
= 13 quetiapine	6
= 16 fluphenazine	5
= 16 fluvoxamine	5
= 18 bupropion	4
= 18 diazepam	4
= 18 thioridazine	4

NON-ACCIDENTAL OVERDOSE

Drug Substance	No of Reports
1 paroxetine	36
2 olanzapine	29
= 3 paracetamol	28
= 3 venlafaxine	28
= 5 bupropion	17
= 5 clozapine	17
= 5 fluoxetine	17
8 sertraline	15
9 citalopram	14
= 10 carbamazepine	9
= 10 codeine	9
=12 amitriptyline	8
=12 dothiepin	8
=12 zopiclone	8
=12 dextropropoxyphene	8
16 quetiapine	7
17 moclobemide	6

OVERDOSE N.O.S.

Drug Substance	No of Reports
1 clozapine	109
2 venlafaxine	50
3 paroxetine	41
4 fluoxetine	35
5 paracetamol	29
6 bupropion	26
= 7 citalopram	24
= 7 zopiclone	24
9 olanzapine	19
= 10 dothiepin	18
= 10 sertraline	18
12 tramadol	16
13 quetiapine	14
14 amitriptyline	13
= 15 aspirin	11
= 15 carbamazapine	11
= 15 diazepam	11
18 diamorphine	10
= 19 dihydrocodeine	8
= 19 risperidone	8

SUICIDAL IDEATION

Drug Substance	No of Rpts
1 fluoxetine	125
2 bupropion	74
3 paroxetine	57
4 isotretinoin	18
5 mefloquine	17
= 6 citalopram	11
= 6 efavirenz	11
= 6 mirtazapine	11
= 6 sertraline	11
= 6 venlafaxine	11
11 zopiclone	8
= 12 medroxyprogesterone	7
= 12 oestradiol	7
= 12 topiramate	7
= 15 levonorgestrel	6
= 15 nefazadone	6
= 15 norethisterone	6
= 15 simvastatin	6
= 19 amlodipine	5
= 19 atenolol	5
= 19 clarithromycin	5
= 19 etoricoxib	5
= 19 fluvoxamine	5
= 19 gabapentin	5
= 19 lamotrigine	5
= 19 levetiracetam	5
= 19 rofecoxib	5